Skinner MK, Manikkam M, Haque MM, Zhang B, Savenkova MI, "Epigenetic transgenerational inheritance of somatic transcriptomes and epigenetic control regions," Genome Biology, 2012, 13:10, DOI: 10.1186/gb-2012-13-10-r91. ABSTRACT: BACKGROUND: Environmentally induced epigenetic transgenerational inheritance of adult onset disease involves a variety of…
Skinner MK, Guerrero-Bosagna C, Haque M, Nilsson E, Bhandari R, McCarrey JR, "Environmentally induced transgenerational epigenetic reprogramming of primordial germ cells and the subsequent germ line," PLoS One, 2013, 8:7, DOI: 10.1371/journal.pone.0066318. (Erratum in PLoS One. 2013;8(7). DOI:10.1371/annotation/7683bb48-85db-4c7e-87c0-304a7d53a587.) ABSTRACT: A number of…
Skinner MK, Manikkam M, Tracey R, Guerrero-Bosagna C, Haque M, Nilsson EE, "Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity," BMC Medicine, 2013, 11:228, DOI: 10.1186/1741-7015-11-228. ABSTRACT: BACKGROUND: Ancestral environmental exposures to a variety of environmental factors and toxicants…
Rissman EF, Adli M, "Minireview: transgenerational epigenetic inheritance: focus on endocrine disrupting compounds," Endocrinology, 2014, 155:8, DOI: 10.1210/en.2014-1123. ABSTRACT: The idea that what we eat, feel, and experience influences our physical and mental state and can be transmitted to our offspring and…
Nilsson E, Larsen G, Manikkam M, Guerrero-Bosagna C, Savenkova MI, Skinner MK, "Environmentally induced epigenetic transgenerational inheritance of ovarian disease," PLoS ONE, 2012, 7:5, DOI: 10.1371/journal.pone.0036129. ABSTRACT: The actions of environmental toxicants and relevant mixtures in promoting the epigenetic transgenerational…
Manikkam M, Guerrero-Bosagna C, Tracey R, Haque MM, Skinner MK, “Transgenerational actions of environmental compounds on reproductive disease and identification of epigenetic biomarkers of ancestral exposures,” PLoS One, 2012, 7:2. ABSTRACT: Environmental factors during fetal development can induce a permanent epigenetic…
Manikkam M, Tracey R, Guerrero-Bosagna C, Skinner MK, “Pesticide and insect repellent mixture (permethrin and DEET) induces epigenetic transgenerational inheritance of disease and sperm epimutations,” Reproductive Toxicology, 2012, 34:4, DOI: 10.1016/j.reprotox.2012.08.010. ABSTRACT: Environmental compounds are known to promote epigenetic transgenerational inheritance…
Kabasenche WP, Skinner MK, “DDT, epigenetic harm, and transgenerational environmental justice,” Environmental Health, 2014, 13:62, DOI: 10.1186/1476-069X-13-62. ABSTRACT: Although the environmentally harmful effects of widespread dichlorodiphenyltrichloroethane (DDT) use became well-known following Rachel Carson’s Silent Spring (1962), its human health effects have more…
Heindel JJ, “Role of exposure to environmental chemicals in the developmental basis of reproductive disease and dysfunction,” Seminars in Reproductive Medicine, 2006, 24:3. ABSTRACT: There is a paradigm shift in science at present that indicates that the onset of many diseases, including…
Collotta, M, Bertazzi, PA, Bollati, V, “Epigenetics and pesticides,” Toxicology, 2013, 307, DOI: 10.1016/j.tox.2013.01.017. ABSTRACT: Pesticides, a wide class of environmental contaminants, may cause both acute and delayed health effects in exposed subjects. These effects can range from simple irritation of the skin…